Who This Is For
- Adults seeking a strong antioxidant through glutathione precursor supplementation
- Those wanting liver protection and support for Phase II detoxification pathways
- Those seeking respiratory health support and help clearing excess mucus
- Those wanting the most effective oral strategy for raising intracellular glutathione levels
- Vegans and vegetarians seeking a fully plant-based capsule formula
- Those seeking a Canadian made supplement with full Health Canada licensing
Source
N-Acetyl-L-Cysteine (NAC) is synthetically produced by acetylation of L-Cysteine, an amino acid found naturally in protein-containing foods including meat, poultry, eggs, and dairy. The resulting NAC is chemically identical to the compound used in pharmaceutical applications worldwide and is significantly more stable and bioavailable than L-Cysteine itself. Synthetic production ensures pharmaceutical grade purity and consistent potency.
NAC and Glutathione
Glutathione (GSH) is a tripeptide composed of glutamate, cysteine, and glycine. It is the most abundant intracellular antioxidant in the body, with the highest concentrations in the liver. Of the three amino acid substrates required for glutathione synthesis, cysteine is the least abundant intracellularly and is therefore the rate-limiting substrate. When cysteine availability is low, glutathione synthesis slows regardless of the availability of glutamate and glycine. NAC supplementation increases intracellular cysteine availability, directly supporting glutathione synthesis. Oral glutathione supplements are broken down by intestinal peptidases before absorption and do not efficiently raise intracellular glutathione. NAC, by contrast, is absorbed intact and converted to cysteine intracellularly, making it the most effective oral strategy for raising intracellular glutathione levels.
Key Benefits
- Strong antioxidant Glutathione is the body's primary endogenous antioxidant. NAC replenishes intracellular glutathione by providing cysteine, the rate-limiting substrate for glutathione synthesis. Health Canada licensed use under NPN 80078286.
- Liver protection by boosting glutathione levels The liver has the highest glutathione concentration of any organ. Hepatic glutathione is essential for Phase II detoxification via glutathione S-transferase enzymes, which conjugate reactive metabolites and xenobiotics for excretion. NAC replenishes hepatic glutathione, supporting the liver's detoxification capacity. Health Canada licensed use under NPN 80078286.
- Detoxification support Glutathione S-transferases conjugate glutathione to reactive Phase I metabolites, drug metabolites, and environmental toxins, making them water-soluble for excretion via bile or urine. Health Canada licensed use under NPN 80078286.
- Respiratory health and mucolytic action NAC's free thiol (SH) group cleaves disulfide bonds between mucin glycoproteins, reducing mucus viscosity and helping clear excess mucus from the airways. Health Canada licensed use under NPN 80078286.
- 600mg per capsule Single daily capsule with meals.
- Health Canada licensed NPN 80078286. Made in Canada.
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